@jonas Hello! I also have a similar problem, though with a different set up.

Ubuntu 20.04 & 22.04 (Just upgraded- same problem on both distros)
JDS Labs Element II DAC/Amp
Brave & Firefox browsers

Strawberry Backend Settings:
Output to a sound card via ALSA
Device JDS Labs Element II USB Audio

hw:1,0

ALSA plugin: hw selected, out of the following options

hw plughw pcm

I'm trying to play high resolution FLAC files (192khz/24bit), so I'd prefer to avoid downsampling to 48khz if possible.

Thank you for your time, and thanks for the work you and the other developers put into strawberry- I wouldn't want to use anything else. 🙂
-GarethFuller